Human TNKS1 in complex with 3-[4-(1-Hydroxy-1-methyl-ethyl)-phenyl]-6-methyl-2H-pyrrolo[1,2-a]pyrazin-1-one
收藏Protein Data Bank Japan2024-11-20 更新2026-04-19 收录
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Human TNKS1 in complex with 3-[4-(1-Hydroxy-1-methyl-ethyl)-phenyl]-6-methyl-2H-pyrrolo[1,2-a]pyrazin-1-one Descriptor: 6-methyl-3-[4-(2-oxidanylpropan-2-yl)phenyl]-4~{H}-pyrrolo[1,2-a]pyrazin-1-one, ACETATE ION, Poly [ADP-ribose] polymerase, ... Authors: Musil, D, Lehmann, M, Buchstaller, H.-P. Deposit date: 2021-04-28 Release date: 2021-07-28 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (1.432 Å) Cite: Optimization of a Screening Hit toward M2912, an Oral Tankyrase Inhibitor with Antitumor Activity in Colorectal Cancer Models. J.Med.Chem., 64, 2021
创建时间：
2021-04-28
