Characterization of the salivary microbiome in healthy individuals under fatigue status

As researchers specializing in the exploration of the human microbiome, with a focus on its role in maintaining human health, we conducted a comprehensive study on the characteristics of the microbiome in healthy individuals under fatigue conditions.Hence, in this study, we examined the relationship between the oral microbiome and fatigue by performing 16S rRNA high-throughput sequencing to analyze the oral microbiome composition in a cohort of fatigued healthy individuals. The phenotypes and metabolic pathways of the oral microbiome were predicted using bioinformatics tools to determine how these changes will influence oral health, the central nervous system (CNS), and overall systemic health.