Effects of Conditional Egfr deletion on transcriptome of the mouse cerebral cortex. Effects of Conditional Egfr deletion on transcriptome of the mouse cerebral cortex

To investigate the role of Egfr in the cerebreal cortex and hippocampal formation we conditionally deleted it using a floxed allele in combination with the Nestin-cre transgene. Cortices at P5 post-natal stage were harvested and split into rostral and caudal halves and RNA extracted and sequenced Overall design: Comparison of RNA-seq data between rostral and caudal cortices and hippocampal formation of control brains (EgfrF/+ gentoype) and brain-specific knock of Egfr (Nestin-EgfrF/F).