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Crystal structure of the Fucosylgalactoside alpha N-acetylgalactosaminyltransferase (GTA, cisAB mutant L266G, G268A) in complex with a novel UDP-GalNAc derived inhibitor (3GW and 4GW)

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Protein Data Bank Japan2023-09-13 更新2026-03-21 收录
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Crystal structure of the Fucosylgalactoside alpha N-acetylgalactosaminyltransferase (GTA, cisAB mutant L266G, G268A) in complex with a novel UDP-GalNAc derived inhibitor (3GW and 4GW) Descriptor: 5-(5-formylthiophen-2-yl)uridine 5'-(trihydrogen diphosphate), 5-(5-formylthiophen-2-yl)uridine-5'(2-(acetylamino)-2-deoxy-alpha-D-galactosyl)-diphosphate, GLYCEROL, ... Authors: Palcic, M.M, Jorgensen, R. Deposit date: 2011-12-08 Release date: 2013-01-23 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Base-modified donor analogues reveal novel dynamic features of a glycosyltransferase. J.Biol.Chem., 288, 2013
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2011-12-08
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