Association between Trop-2 functional states and tumor pathobiological parameters.

a: variables analyzed.b: overall distribution for each of the variables included in the study.c: distribution of scores of cytoplasmic Trop-2 expression (low or high).d: distribution of scores of membrane Trop-2 expression (low or high). Both raw (N) and relative (%) frequencies are reported. OR: adjusted odds ratios for intracellular Trop-2 overexpression (high versus low), obtained by multiple logistic regression; categories used as reference have OR = 1. pT: pathological stage. Wald test P values for the mAb (PM) and for the pAb (PP) scores and associated numbers of cases analyzed (nM, nP) are indicated.