Data for: NEUROENDOCRINE HYPERPLASIA IN A LARGE COMPOSITE ADENOMA- MICROCARCINOID Case Report and Literature Review on Colonic Adenoma-Microcarcinoids/Carcinoids.

A composite adenoma-microcarcinoid is an intestinal neoplasm consisting of intermixed adenomatous and well-differentiated neuroendocrine components. Although subtle neuroendocrine differentiation is commonly seen in intestinal adenomas, colorectal tumors containing a significant percentage of morphologically recognizable neuroendocrine cells are uncommon. Unlike other mixed endocrine-glandular colorectal neoplasms, which are generally malignant, the glandular component of a composite adenoma-microcarcinoid is histologically benign, with a natural history that is generally favorable. We report an unusually large tubular adenoma associated with a microcarcinoid that arises in a backdrop of neuroendocrine hyperplasia, a rare phenomenon that has not been well documented in the literature.

复合腺瘤-微癌是一种由混合的腺瘤性和分化良好的神经内分泌成分组成的肠道新生物。尽管在肠道腺瘤中常可见到微妙的神经内分泌分化，但在形态学上可识别的神经内分泌细胞占较大比例的结直肠癌却是罕见的。与通常为恶性的其他混合内分泌-腺体结直肠癌不同，复合腺瘤-微癌的腺体成分在组织学上表现为良性，其自然病史通常较为有利。本研究报告了一例与微癌相关且伴有神经内分泌增生的异常大管状腺瘤，这是一种在文献中尚未得到充分记录的罕见现象。