Linking chemical and microbial diversity in marine sponges: possible role for Poribacteria as producers of methyl-branched fatty acids.

For the symbiont-rich sponge Cacospongia mycofijiensis, a source of the tubulin-inhibiting fijianolides (=laulimalides), near-exhaustive large-scale sequencing of PKS gene-derived PCR amplicons was conducted.