Evolved isolates methylome

NIAID Data Ecosystem2026-05-01 收录

表观遗传学

DNA甲基化分析

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA1104141 数据链接链接失效反馈

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For methylome analyses, evolved cells on days 15 and 25 were obtained methylome data using single-molecule real-time (SMRT) sequencing (PacBio).

创建时间：

2024-04-24

DOT1L controls NK cell maturation and lineage integrity [RNA-seq D0 & D2]. DOT1L controls NK cell maturation and lineage integrity [RNA-seq D0 & D2]

细胞免疫学

表观遗传学

Epigenetic modifiers are promising targets to improve therapies in patients with cancer. Targeting the methyltransferase DOT1L with small molecule inhibitors has shown promising effects on the control

NIAID Data Ecosystem40

H3K27ac peaks displaying a significant increase in read counts in laboring samples relative to d15 samples.

表观遗传学

分娩相关基因调控

d, day; H3K27ac, H3 acetylation on lysine residue 27. (XLSX)

NIAID Data Ecosystem20

Natural depletion of H1 in sex cells causes DNA demethylation, heterochromatin decondensation and transposon activation

转座子调控

DNA甲基化分析

Transposable elements (TEs) are largely inactive. Interestingly, a subset of TEs are naturally expressed in the vegetative cell (VC) of the male gametophyte, pollen in Arabidopsis. However, the extent

NIAID Data Ecosystem00

Summary of COL1A2 , THBS1 , TNFRSF10D and UCHL1 methylation in melanocytes, melanoma cell lines, fresh-frozen melanoma tumors and other cancer cell lines.

黑色素瘤甲基化

表观遗传学

Ratios to melanocytes are presented for the % of methylation in melanoma cell lines and melanocytes (MM/mel) and the fresh-frozen tumors (FT/mel). MM malignant melanoma. mel melanocytes. FT fresh-froz

NIAID Data Ecosystem30

Additional file 8: of Novel age-associated DNA methylation changes and epigenetic age acceleration in middle-aged African Americans and whites

表观遗传学

年龄相关疾病

Table S6. Top enrichment results of age-associated differentially hypermethylated CpG positions (aDMPs) for age-related diseases and quantitative traits. (XLSX 12 kb)

Figshare2019-08-19 更新00

Evolved isolates methylome

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