The concentration of each drug was determined according to which it is administered in clinical practice. SD: Standard Deviation calculated from three independent repeats (n = 3). Selectivity: Drugs c
acompounds to have a reasonable propability of being well absorbt their logP value must not be greater than 5.0. bmore than 80% of the drugs on the market have a (estimated) logS value greater than −4
A multivariate analysis of drugs on the Swedish market was the basis for the selection of a small, physicochemically diverse set of 24 drug compounds. Factors such as structural diversity, commercial