Circadian-dependent responses to cisplatin treatment in a mouse model of hepatoma

NIAID Data Ecosystem2026-05-02 收录

时间治疗学

肿瘤药物疗效

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We have used a mouse model of liver cancer and analyzed responses to the anticancer drug cisplatin as a function of the time of day of cisplatin administration.

创建时间：

2025-02-07

Design and optimization of self-microemulsifying drug delivery system (SMEDDS) of felodipine for chronotherapeutic application

药物递送系统

时间治疗学

The objective of this research work was to design, develop and optimize the self micro-emulsifying drug delivery system (SMEDDS) of Felodipine (FL) filled in hard gelatine capsule coated with polymer

DataCite Commons2022-06-09 更新90

Circadian clock, carcinogenesis, chronochemotherapy connections. Circadian clock, carcinogenesis, chronochemotherapy connections

生物钟

时间治疗学

The circadian clock controls the expression of nearly 50% of protein coding genes in mice, and most likely in humans as well. Therefore, disruption of the circadian clock is presumed to have serious p

NIAID Data Ecosystem30

A circadian gene expression atlas in mammals assayed by RNA-seq. Mus musculus

生物钟基因调控

时间治疗学

To characterize the role of the circadian clock in mouse physiology and behavior, we used RNA-seq and DNA arrays to quantify the transcriptomes of 12 mouse organs over time. We found 43% of all protei

NIAID Data Ecosystem30

RGD-A- TNF Multiple Dose Study: Patient Data and Tumor Responses

肿瘤药物疗效

动物模型研究

FS: fibrosarcoma; OS: osteosarcoma; PNST: peripheral nerve sheath tumor (malignant); SCC: squamous cell carcinoma; S-C MS: subcutaneous myxosarcoma; MLT: multi-lobular tumor; Mel: LN mets: melanoma ly

NIAID Data Ecosystem60

Circadian rhythm-dependent programs control inflammatory responses and drug metabolism in primary human hepatocytes II.. Circadian rhythm-dependent programs control inflammatory responses and drug metabolism in primary human hepatocytes II.

肝脏昼夜节律调控

时间治疗学

Various aspects of physiology and cell function present self-sustained ~24h variations termed circadian rhythms, enabling anticipation and adaptation to the 24-h cycle produced by the Earth’s rotation

NIAID Data Ecosystem30

Circadian-dependent responses to cisplatin treatment in a mouse model of hepatoma

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