RSV proteins and epitopes used in subunit vaccine formulation.

aProtein product included in subunit vaccine formulations, as abbreviated in the current paper. bHRSV Long strain (GenBank accession no. AY911262) was used to construct recombinant protein. cFull length HRSV M2-1 protein (Long strain). dFull length HRSV P protein (Long strain). eBRSV strain 9402022 (Larsen et al. 1998) was used to construct recombinant protein. fSelected residues were recombinantly attached to the N or C terminus of HRSV N protein (Long strain) and co-expresses with a fragment of HRSV P protein (Long strain, AA residues 161–241) to form N-nanorings with attached epitopes (eN) on each of 10 or 11 protomers. gAntigenic site II (AA residues 422–438) on F, as described by Chargelegue et al. (1998).