X-ray crystal structure of compound 1 bound to human CHK1 kinase domain
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X-ray crystal structure of compound 1 bound to human CHK1 kinase domain Descriptor: 2-(2,3-dihydro-1-benzofuran-5-yl)-N-[2-(piperazin-1-yl)phenyl]-1,3-thiazole-4-carboxamide, Serine/threonine-protein kinase Chk1 Authors: Fischmann, T.O. Deposit date: 2011-10-19 Release date: 2012-01-25 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Discovery of a Novel Series of CHK1 Kinase Inhibitors with Distinctive Hinge Binding Mode ACS MED.CHEM.LETT., 2012
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2011-10-19
