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crystal structure of BRD2-BD1 in complex with guanosine analog

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Protein Data Bank Japan2023-08-16 更新2026-04-25 收录
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crystal structure of BRD2-BD1 in complex with guanosine analog Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 9-HYROXYETHOXYMETHYLGUANINE, Bromodomain-containing protein 2, ... Authors: Padmanabhan, B, Arole, A, Deshmukh, P, Ashok, S, Mathur, S. Deposit date: 2021-10-22 Release date: 2023-02-01 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural and biochemical insights into purine-based drug molecules in hBRD2 delineate a unique binding mode opening new vistas in the design of inhibitors of the BET family. Acta Crystallogr D Struct Biol, 79, 2023
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2021-10-22
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