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The Interferon Resistance of Transmitted HIV-1 is Likely a Consequence of Enhanced Replicative Fitness
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2022-08-06
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The Interferon Resistance of Transmitted HIV-1 is Possibly a Consequence of Enhanced Replicative Fitness
Underlying data for a paper
DataCite Commons2022-11-09 更新50
HIV-1 fitness. The Apparent Interferon Resistance of Transmitted HIV-1 is Likely A Consequence of Enhanced Replicative Fitness
HIV-1 transmission via sexual exposure is an inefficient process. When successful transmission does occur, newly infected individuals are colonized by the descendants of either a single virion or a ve
NIAID Data Ecosystem30
Human immunodeficiency virus 1 strain:NL4-3 Raw sequence reads
This is a long term evolution experiment with HIV-1 NL4-3. We serially transferred four HIV-1 population 90 times (315 days). Two populations were grown on MT-2 T cells and two populations on MT-4 T c
NIAID Data Ecosystem10
Genotypic and Functional Impact of HIV-1 Adaptation to Its Host Population during the North American Epidemic
HLA-restricted immune escape mutations that persist following HIV transmission could gradually spread through the viral population, thereby compromising host antiviral immunity as the epidemic progres
NIAID Data Ecosystem30
Relaxation of Adaptive Evolution during the HIV-1 Infection Owing to Reduction of CD4+ T Cell Counts
BackgroundThe first stages of HIV-1 infection are essential to establish the diversity of virus population within host. It has been suggested that adaptation to host cells and antibody evasion are the
NIAID Data Ecosystem20
