Levels of RNA and protein for different proteins of M-R systems of M. pneumoniae.

Data for microarrays and tiling was taken from Guell et al [43]. Data regarding protein copy number was taken from Maier et al. [44] and from unpublished MS analysis done by M. Lluch-Senar. ORFs labeled with an asterisk indicate proteins found to bind to DNA by doing affinity chromatography with a DNA column followed by salt elution and MS (manuscript in preparation). HsdM (Methyltransferase), HdsS (DNA specificity recognition protein), HdsR (Restriction enzyme), M.MpnI (name assigned to the methyltransferase that recognizes 5′-CTAT-3′), M.MpnII (name assigned to the putative methyltransferase of the Type I motif) and S.MpnII (HsdS subunit associated to Type I restriction modification system).δEssential genome of M. pneumoniae has been determined by using a library of minitransposon mutants (manuscript in preparation Lluch-Senar, M. et al.). NE, non essential gene; E, essential gene.