Hemagglutination inhibition (HI) titers.
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(A–C) Ferrets were immunized with commercial human TIV on days 0 and 21, and challenged with Perth/16 on day 35. Blood samples were collected on days 0, 21, 35, 42, and 49. (D–F) Ferrets were challenged with Perth/16 and NY/21 on day 0. Blood samples were collected on days 0, 9 and 14. HI assays were performed using (A, D) A/Victoria/210/2009 (H3N2), (B, E) A/California/07/2009 (H1N1pdm), and (C, F) B/Brisbane/60/2008 antigen controls. “Mock”, unvaccinated mock-infected animals; “Naïve”, unvaccinated animals challenged with Perth/16; “TIV”, vaccinated animals challenged with Perth/16; “H3N2”, unvaccinated animals challenged with Perth/16; “H1N1pdm”, unvaccinated animals challenged with NY/21. † indicates p
创建时间:
2016-02-23



