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Wild-type p53 enhances efficiency of simian virus 40 large-T-antigen-induced cellular transformation

ChEBI2009-07-18 更新2026-07-21 收录

病毒诱导细胞转化

p53肿瘤抑制基因功能

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-17178 数据链接链接失效反馈

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资源简介：

Wild-type p53 enhances efficiency of simian virus 40 large-T-antigen-induced cellular transformation

应用场景：

创建时间：

2009-07-18

基因表达分析

病毒诱导细胞转化

To investigate the role of AP-1 in Src-mediated transformation, we undertook a gene profiling study to characterize the transcriptomes of v-Src-transformed CEF expressing either the c-Jun dominant-neg

NIAID Data Ecosystem70

Profiles and ChIP on chip experiments with dl1500 virus (expressing WT small e1a), R2G and deltaCR2 mutant viruses

病毒诱导细胞转化

表观遗传调控

Adenovirus e1a induces quiescent human cells to divide. We found that e1a causes global relocalization of the RB-proteins (RB, p130, p107) and p300/CBP histone acetyltransferases on promoters that res

NIAID Data Ecosystem50

Expression profiles and ChIP on chip genomewide experiments with dl1500 virus (expressing WT small e1a).

病毒诱导细胞转化

表观遗传调控

NIAID Data Ecosystem30

Expression profiles and ChIP on chip genomewide experiments with deltaCR2 mutant virus . Homo sapiens

病毒诱导细胞转化

表观遗传调控

NIAID Data Ecosystem60

Transformation of primary mouse embryo fibroblasts by SV40 parental and microRNA-negative viruses.

病毒诱导细胞转化

SV40病毒

SV40, simian virus 40. aReplicate plates (n = 4–6) were harvested per virus at each time point. Numbers of transformed foci per 1×105 cells infected by each virus were normalized to the value for the

NIAID Data Ecosystem40

Wild-type p53 enhances efficiency of simian virus 40 large-T-antigen-induced cellular transformation

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