N‑Heterocyclic Carbenes Derived from Guanosine: Synthesis and Evidences of Their Antiproliferative Activity
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https://figshare.com/articles/dataset/N_Heterocyclic_Carbenes_Derived_from_Guanosine_Synthesis_and_Evidences_of_Their_Antiproliferative_Activity/7352822
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资源简介:
Palladium(II) and platinum(II) complexes
bearing N-heterocyclic
carbenes derived from guanosine are synthesized via oxidative addition,
followed by protonation in the presence of acid. Cytotoxicity of the
compounds is evaluated in several cell lines. Compounds 2a, 2b, and 3a are selective for glioblastoma
U251 cells and are nontoxic toward healthy human embryonic kidney
(HEK293) cells.
创建时间:
2018-11-16



