five

N‑Heterocyclic Carbenes Derived from Guanosine: Synthesis and Evidences of Their Antiproliferative Activity

收藏
NIAID Data Ecosystem2026-03-10 收录
下载链接:
https://figshare.com/articles/dataset/N_Heterocyclic_Carbenes_Derived_from_Guanosine_Synthesis_and_Evidences_of_Their_Antiproliferative_Activity/7352822
下载链接
链接失效反馈
官方服务:
资源简介:
Palladium­(II) and platinum­(II) complexes bearing N-heterocyclic carbenes derived from guanosine are synthesized via oxidative addition, followed by protonation in the presence of acid. Cytotoxicity of the compounds is evaluated in several cell lines. Compounds 2a, 2b, and 3a are selective for glioblastoma U251 cells and are nontoxic toward healthy human embryonic kidney (HEK293) cells.
创建时间:
2018-11-16
二维码
社区交流群
二维码
科研交流群
商业服务