Functional enrichment analysis (cell types).

The table shows the functional enrichment analysis for genes associated with each cell type. The table is organized as S4 Table, with one difference: cell type, rather than “tissue 1” and “tissue 2” is reported. For each cell type, we determined the association (effect size) between its proportion and the expression of each gene, and used the effect sizes of all expressed genes as input for gene set enrichment analysis (GSEA). We observed that the most significantly enriched gene sets corresponded to the main function associated with each cell type, including mitochondrial and cell respiration functions for cardiac muscle, immune response for immune cells, cytoskeleton and actin binding for smooth muscle. Only significant gene sets are reported (FDR < 0.05). The differential expression analysis of gene sets can be found at https://doi.org/10.6084/m9.figshare.13537343. (CSV)