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Developmental chromatin programs determine oncogenic competence in melanoma [RNA-seq II]. Developmental chromatin programs determine oncogenic competence in melanoma [RNA-seq II]

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA721736
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Transcriptional profile of 3xKO dox melanocytes and 3xKO ATAD2 dox melanocytes Overall design: hPSC-derived melanocytes were infected with a lentivirus (Tomato or ATAD2) and selected for 1 week with blastocidin. After selection, the hPSC-derived melanocytes were treated for 72h with doxycycline to induce expression of BRAFV600E. Roughly 500'000 cells were collected per condition.
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2021-04-13
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