Experimental Data on In Vitro Maturation of Cumulus-Enclosed Oocites Exposed to Polystyrene Nanoplastics

In recent years, there is increasing concern about the potential harmful effects of nanoplastics (NPs) on mammalian reproductive processes, especially regarding their impact on gametes. Given the limited research on NPs effect on mammalian oocyte, this study investigated the biological impact of increasing concentrations of 100 nm polystyrene nanoplastics (PS-NPs)(5, 50, 100 and 200 μg/mL) on cumulus-enclosed oocytes (COCs), using an in vitro model of pig oocyte maturation (IVM).
These data sets contain the raw data on nuclear maturation, cytoplasmic maturation and developmental competence of oocytes, intracellular oocyte levels of glutathione (GSH) and reactive oxygen species (ROS), and steroidogenic activity of cumulus cells (CCs).