Additional file 2 of Vulnerability to low-dose combination of irinotecan and niraparib in ATM-mutated colorectal cancer

Additional file 2: Supplementary table 2. Mutational profiles HRR genes across the cell line panel. 29 genes (CHEK1, CHEK2, RAD51, BRCA1, BRCA2, BAP1, POLQ, ATM, ATR, MDC1, PARP1, FANCF, FANCM, BRIP1, FANCE, WRN, CDK12, MDC1, FAN1, NBN, FANCA, RAD51C, RAD51D, EXO1, RBBP8, FANCD2, NONO, SMC5, USP11) with relevance in the HRD phenotype (Riaz, Nat Commun 2017) were analyzed. Mutational profiles were obtained from cBio-portal using the Cancer Cell Line Encyclopaedia (CCLE) dataset [last accessed June 20th 2020].