MetaboLights MTBLS17 - GNPS Utilization of Metabolomics to Identify Serum Biomarkers for Hepatocellular Carcinoma in Patients with Liver Cirrhosis

This data set is downloaded from MetaboLights (http://www.ebi.ac.uk/metabolights/) accession number MTBLS17 Abstract:Characterizing the metabolic changes pertaining to hepatocellular carcinoma (HCC) in patients with liver cirrhosis is believed to contribute towards early detection, treatment, and understanding of the molecular mechanisms of HCC. we compare metabolite levels in sera of 78 HCC cases with 184 cirrhotic controls by using ultra performance liquid chromatography coupled with a hybrid quadrupole time-of-flight mass spectrometry (UPLC-QTOF MS). Several candidate metabolic biomarkers for early detection of HCC cases in high risk population of cirrhotic patients are identified using mass spectrum.