Tricomplex of RMC-6236, KRAS G12D, and CypA
收藏Protein Data Bank Japan2024-06-12 更新2026-04-19 收录
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https://pdbj.org/mine/summary/9ax6
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Tricomplex of RMC-6236, KRAS G12D, and CypA Descriptor: (1R,2S)-N-[(1P,7S,9S,13R,20M)-21-ethyl-20-{2-[(1R)-1-methoxyethyl]-5-(4-methylpiperazin-1-yl)pyridin-3-yl}-17,17-dimethyl-8,14-dioxo-15-oxa-4-thia-9,21,27,28-tetraazapentacyclo[17.5.2.1~2,5~.1~9,13~.0~22,26~]octacosa-1(24),2,5(28),19,22,25-hexaen-7-yl]-2-methylcyclopropane-1-carboxamide, GTPase KRas, MAGNESIUM ION, ... Authors: Tomlinson, A.C.A, Saldajeno-Concar, M, Knox, J.E, Yano, J.K. Deposit date: 2024-03-05 Release date: 2024-04-17 Last modified: 2024-06-12 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Translational and Therapeutic Evaluation of RAS-GTP Inhibition by RMC-6236 in RAS-Driven Cancers. Cancer Discov, 14, 2024
创建时间：
2024-03-05
