Transcriptomic analysis of cspC deficient Acinetobacter baumannii

This study examined the response of A. baumannii to cspC disruption via transposon mutagenesis. The goal was to gain insight into how a cold shock protein highly expressed within A. baumannii biofilms, CspC, functioned and identify pathways in which it may be involved. A. baumannii RNA was extracted to compare global gene expression of two samples: AB5075 wild type and AB5075 cspC transposon mutant. AB5075 wild type serves as the parental control strain. Each sample was generated by pooling three independent biological replicate RNA preps.