Crystal structure of bruton's tyrosine kinase in complex with inhibitor CGI1746
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Crystal structure of bruton's tyrosine kinase in complex with inhibitor CGI1746 Descriptor: 4-tert-butyl-N-[2-methyl-3-(4-methyl-6-{[4-(morpholin-4-ylcarbonyl)phenyl]amino}-5-oxo-4,5-dihydropyrazin-2-yl)phenyl]benzamide, BETA-MERCAPTOETHANOL, SULFATE ION, ... Authors: Davies, D.R, Gallion, S.L, Staker, B.L. Deposit date: 2010-08-10 Release date: 2010-11-03 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.8 Å) Cite: A novel, specific Btk inhibitor antagonizes BCR and Fc[gamma]R signaling and suppresses inflammatory arthritis To be Published
创建时间：
2010-08-10
