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Adipose tissue NAD+ biosynthesis is required for regulating adaptive thermogenesis and whole-body energy homeostasis in mice

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We evaluated the effects of NAMPT (nicotinamide phosphoribosyltransferase) knockout on transcriptome in brown adipose tissue (BAT) by analyzing BAT obtained from control (Nampt-flox/flox, F1-F4) and adipocyte-specific Nampt knockout (ANKO, A1-A4) mice. We analyzed BAT obtained from 4 control mice and 4 ANKO mice.

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