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Additional file 2 of Comparative gene expression profiling between optic nerve and spinal cord injury in Xenopus laevis reveals a core set of genes inherent in successful regeneration of vertebrate central nervous system axons

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Mendeley Data2024-06-25 更新2024-06-27 收录
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https://springernature.figshare.com/articles/Additional_file_2_of_Comparative_gene_expression_profiling_between_optic_nerve_and_spinal_cord_injury_in_Xenopus_laevis_reveals_a_core_set_of_genes_inherent_in_successful_regeneration_of_vertebrate_central_nervous_system_axons/12768841
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Additional file 2. DESeq2 differential expression data. Tabs are for each injury condition and time point vs. their relevant controls (N = 3 biological replicates, each). Tabs PW1–3) Tadpole spinal cord injury (SCI) hindbrain vs. age-matched, unoperated control hindbrain at 3 days, 1 week, and 3 weeks, respectively; PW4–6) Juvenile frog SCI hindbrain at 3 days, 1 week, and 3 weeks vs. unoperated control hindbrain; PW7–9) juvenile frog optic nerve crush (ONC) eye vs. the contralateral unoperated eye at 3 days, 11 days, and 3 weeks, respectively. Columns: A - Gene Name; B, baseMean - mean counts of all samples, normalized for sequencing depth. It does not take into account gene length and is used for estimating the dispersion of a gene; C, log2FoldChange - log2(control/experimental); in this analysis, negative values represent injury induced increases relative to control); D, lfcSE - Standard Error of the log2 fold change; E, stat - log2FoldChange/lfcSE; F, pvalue - the probability of the null hypothesis for an individual gene (i.e., variance among replicates = variance between conditions); G, padj - false discovery rate-adjusted (FDR) p-value.
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2023-06-28
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