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Transcriptome analysis of peripheral lymphoid tissue immediately before and after the detection of PrPSc in sheep scrapie 2

ChEBI2014-04-06 更新2026-07-21 收录

朊病毒疾病分子机制

羊痒病转录组学

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-2330 数据链接链接失效反馈

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资源简介：

Transcriptome analysis of peripheral lymphoid tissue immediately before and after the detection of PrPSc in sheep scrapie 2

应用场景：

创建时间：

2014-04-06

朊病毒疾病分子机制

时序基因表达分析

Screen for temporal changes in gene expression of damage-associated molecular pattern (DAMP) recognition receptors and associated proteins during infection with scrapie strain 22L.

NIAID Data Ecosystem60

The cell type resolved mouse transcriptome in neuron-enriched brain tissues from the hippocampus and cerebellum during prion disease. The cell type resolved mouse transcriptome in neuron-enriched brain tissues from the hippocampus and cerebellum during prion disease

朊病毒疾病分子机制

元转录组分析

Multiple cell types and complex connection networks are an intrinsic feature of brain tissue. In this study we used expression profiling of homogeneous cell populations from specific microscopic regio

NIAID Data Ecosystem40

Upregulation of the Genes Encoding Lysosomal Hydrolases, a Perforin-Like Protein, and Peroxidases in the Brains of Mice Affected with an Experimental Prion Disease

朊病毒疾病分子机制

神经退行性疾病基因

In an attempt to identify the molecules involved in the pathogenesis of prion diseases, we performed cDNA subtraction on the brain tissues of mice affected with an experimental prion disease and the u

PubMed Central20

Transcriptome analysis of microglia and astrocytes in prion-infected mice by RNA-seq

神经细胞转录组学

朊病毒疾病分子机制

Glial activation that is hallmark in prion disease precedes neurodegeneration and the onset of clinical disease. To estimate activation state of microglia and astrocytes in prion disease, cell-specifi

NIAID Data Ecosystem40

Prion-induced gene expression changes.

朊病毒疾病分子机制

细胞类型特异性基因表达

Table containing 3,723 genes that are changing significantly (|log2FC| > 0.5 and FDR Fig 1). Shown are GeneID, cell type enrichment if applicable (_NE = not enriched; AS = astrocytes; EC = endothelial

Figshare2020-06-29 更新40

Transcriptome analysis of peripheral lymphoid tissue immediately before and after the detection of PrPSc in sheep scrapie 2

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