AKT signaling mediates the cellular adaptation to LAT1 pharmacologic inhibition in pancreatic ductal adenocarcinoma.
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https://www.omicsdi.org/dataset/jpost/PXD034389
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To characterize the changes of phosphorylation signaling cascades induced by LAT1 inhibition in MIA PaCa-2 cells treated with LAT1 specific inhibitor JPH203, immobilized metal affinity chromatography and liquid chromatography-tandem mass spectrometry with MS2-based quantitation of tandem mass tag were utilized.
To characterize the changes of protein expressions induced by LAT1 inhibition and AKT inhibition in MIA PaCa-2 cells exposed to LAT1 specific inhibitor JPH203 with or without AKT inhibitor MK-2206, immobilized metal affinity chromatography and liquid chromatography-tandem mass spectrometry with MS2-based quantitation of tandem mass tag were utilized.
创建时间：
2024-04-15
