Interleukin-17 governs hypoxic adaptation of injured epithelium [bulk RNA-seq]

RORgt deficency impaired wound re-epithelialization. We adopted low-input RNA-seq of purified wound epithelium to explore the underlying epithelial cell functional difference between wild type and RORgt deficient mice during wound healing. Overall design: Migrating and nonmigrating wound edge epithelial cells were sorted based on their different surface markers, gene expression were compared between wild type and Rorgt deficient mice with low-input RNA seq.