BIOGRID CURATED DATA FOR TRM8 (Saccharomyces cerevisiae (S288c))

Protein-Protein, Genetic, and Chemical Interactions for TRM8 (Saccharomyces cerevisiae (S288c)) curated by BioGRID (https://thebiogrid.org); DEFINITION: Noncatalytic subunit of a tRNA methyltransferase complex; Trm8p and Trm82p comprise an enzyme that catalyzes a methyl-transfer from S-adenosyl-l-methionine to the N(7) atom of guanine at position 46 in tRNA; Trm8 lacks catalytic activity if not bound to Trm82p

由 BioGRID (https://thebiogrid.org) 精心整理的 TRM8（酿酒酵母 S288c）蛋白质-蛋白质、遗传和化学相互作用数据集；定义：tRNA甲基转移酶复合物的非催化亚基；Trm8p 与 Trm82p 共同构成一种酶，该酶催化 S-腺苷甲硫氨酸上的甲基转移到 tRNA 中第 46 位鸟嘌呤的 N(7) 原子；Trm8 在未与 Trm82p 结合的情况下缺乏催化活性。