Linear mixed model analysis of factors associated with mean differences in the level (in mmol/24h) and change over time (in mmol/24h per year) in urinary creatinine excretion rate.

*mean predicted level in urinary creatinine excretion rate in mmol/24h for 60-yr old non-African and non-diabetic men, with normal BMI (within 18.5 to 25 kg/m2), baseline mGFR of 40 ml/min/1.73 m2, urinary urea of 400 mmol/d and proteinuria in the lowest quartiles.** mean predicted change in urinary creatinine excretion rate in mmol/24h per year in men with stable mGFR and urinary urea, i.e., with no change in level from baseline.† 5 ml/min/1.73 m2 per yr decrease in mGFR and 25 mmol/24h per yr decrease in urinary urea correspond to about three times the mean annual decrease for each variable.Linear mixed model analysis of factors associated with mean differences in the level (in mmol/24h) and change over time (in mmol/24h per year) in urinary creatinine excretion rate.