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The chromatin accessibility landscape of T-Cell Acute Lymphoblastic Leukemia

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE160298
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We investigated the chromatin accessibility landscape of normal T cells and T-Cell Acute Lymphoblastic Leukemia to define the thymocyte development using chromatin accessibility profiles and map the aberrant leukemia-associated accessibility sites in T-ALL. We performed ATAC-seq on 14 normal T cell samples and 35 Leukemia samples including 14 pairs (Diagnosis & Relapse) and another 7 Leukemia daignosis samples. 31 of the leukemia samples also have RNAseq data.
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2024-12-11
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