Crystal structure of EP300 HAT domain in complex with compound 7
收藏Protein Data Bank Japan2023-11-29 更新2026-03-28 收录
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Crystal structure of EP300 HAT domain in complex with compound 7 Descriptor: (2R)-N-(2H-indazol-4-yl)-1-[1-(4-methoxyphenyl)cyclopentyl]carbonyl-pyrrolidine-2-carboxamide, Histone acetyltransferase p300, ZINC ION Authors: Takahashi, M, Hanzawa, H. Deposit date: 2021-09-24 Release date: 2022-04-27 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2 Å) Cite: Discovery of EP300/CBP histone acetyltransferase inhibitors through scaffold hopping of 1,4-oxazepane ring. Bioorg.Med.Chem.Lett., 66, 2022
创建时间：
2021-09-24
