Synthesis of the 1,2,4-Thiadiazole Alkaloid Polyaurine B
收藏NIAID Data Ecosystem2026-03-11 收录
下载链接：
https://figshare.com/articles/dataset/Synthesis_of_the_1_2_4-Thiadiazole_Alkaloid_Polyaurine_B/12136806
下载链接
链接失效反馈官方服务：
资源简介：
A short synthesis of the natural
product polyaurine B is described.
The 1,2,4-thiadiazole heterocycle was assembled using a Cu(II)-mediated
heterocyclization reaction that forges the N–S bond. The final
acylation step to install the methylcarbamate must be conducted under
anhydrous, nonbasic conditions to prevent thiadiazole ring opening
initiated by attack of hydroxide at C-5.
创建时间：
2020-04-16
