The Crystal structure of INSR Tyrosine Kinase in complex with the Inhibitor BI 885578
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The Crystal structure of INSR Tyrosine Kinase in complex with the Inhibitor BI 885578 Descriptor: (5R)-N-(1-{2-[4-(2-methoxyethyl)piperazin-1-yl]ethyl}-1H-pyrazol-3-yl)-5,8-dimethyl-9-phenyl-6,8-dihydro-5H-pyrazolo[3,4-h]quinazolin-2-amine, Insulin receptor Authors: Kessler, D, Zahn, S, Sanderson, M, Wolkerstorfer, B. Deposit date: 2015-09-30 Release date: 2015-10-14 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.264 Å) Cite: BI 885578, a Novel IGF1R/INSR Tyrosine Kinase Inhibitor with Pharmacokinetic Properties That Dissociate Antitumor Efficacy and Perturbation of Glucose Homeostasis. Mol.Cancer Ther., 14, 2015
创建时间：
2015-09-30
