Crystal Structure of the Catalytic Domain of ADAMTS-5 in Complex with an Amino-2-indanol compound
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Crystal Structure of the Catalytic Domain of ADAMTS-5 in Complex with an Amino-2-indanol compound Descriptor: (2R)-N~4~-hydroxy-2-(3-hydroxybenzyl)-N~1~-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]butanediamide, A disintegrin and metalloproteinase with thrombospondin motifs 5, CALCIUM ION, ... Authors: Shieh, H.-S, Williams, J.M, Caspers, N, Mathis, K.J, Tortorella, M.D, Tomasselli, A. Deposit date: 2009-06-22 Release date: 2009-07-07 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Structural and inhibition analysis reveals the mechanism of selectivity of a series of aggrecanase inhibitors J.Biol.Chem., 284, 2009
创建时间:
2009-06-22



