Results of globally fitting five data sets (FIXa proteolytic and amidolytic activity, FIXa intrinsic tryptophan fluorescence Intensity, and ellipticity from Figure 1 and 3, and equilibrium dialysis data) to the two-independent-site model with four global fitting parameters (best fit in bold).

Fits 1–8 were obtained using the condition that that n1 and n2 must be natural numbers. A slightly lower was obtained if we relaxed this requirement (Fit #9). These fits as well as the next best fit (# 6) are compared to data in Figure 6 in the text.