Human glucokinase in complex with novel indazole activator.
收藏Protein Data Bank Japan2024-03-06 更新2026-03-21 收录
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Human glucokinase in complex with novel indazole activator. Descriptor: (2S)-2-[4-(cyclopropylsulfonyl)-1H-indazol-1-yl]-N-(5-fluoro-1,3-thiazol-2-yl)-3-(oxan-4-yl)propanamide, Glucokinase, IODIDE ION, ... Authors: Skene, R.J, Hosfield, D.J. Deposit date: 2017-03-10 Release date: 2017-05-31 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.39 Å) Cite: Discovery of potent and orally active 1,4-disubstituted indazoles as novel allosteric glucokinase activators. Bioorg. Med. Chem. Lett., 27, 2017
创建时间:
2017-03-10



