EGFR(L858R/T790/C797S) in complex with compound 5j
收藏Protein Data Bank Japan2024-01-03 更新2026-04-19 收录
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EGFR(L858R/T790/C797S) in complex with compound 5j Descriptor: CHLORIDE ION, Epidermal growth factor receptor, ~{N}-[3,3-bis(fluoranyl)propyl]-4-[[(2~{S})-butan-2-yl]amino]-6-[[2-(1-cyclopropylsulfonylpyrazol-4-yl)pyrimidin-4-yl]amino]pyridine-3-carboxamide Authors: Nishikawa, Y. Deposit date: 2023-09-14 Release date: 2023-12-20 Last modified: 2024-01-03 Method: X-RAY DIFFRACTION (2.55 Å) Cite: Synthesis, activity, and their relationships of 2,4-diaminonicotinamide derivatives as EGFR inhibitors targeting C797S mutation. Bioorg.Med.Chem.Lett., 98, 2023
创建时间：
2023-09-14
