LFP signals of brain injured anesthetized animals undergoing closed-loop intracortical stimulation
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https://ieee-dataport.org/documents/lfp-signals-brain-injured-anesthetized-animals-undergoing-closed-loop-intracortical
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Activity dependent stimulation (ADS) is a closed loop stimulation technique whose neurophysiological effects are not deeply investigated. Here we explored how Local field potentials (LFP) are impacted by a focal ischemic lesion and, subsequently, by an ADS treatment. Intracortical microelectrode arrays (A4x4-3mm-100-125-177 standard NeuroNexus) were implanted in the rostral forelimb area (RFA) and in the primary somatosensory area (S1) of anaesthetized rats. An ischemic injury was induced in the caudal forelimb area through microinjections of Endothelin-1.The dataset is divided in different phases (as depicted in figure) and two groups: ADS recieved treatment while C recieved sham. Pre-Post lesion data is availabel only for C.
提供机构:
De Michieli, Lorenzo; Carè, Marta; Murphy, Maxwell; Nudo, Randolph; Averna, Alberto; Barban, Federico; Iandolo, Riccardo; Guggenmos, David; Chiappalone, Michela
创建时间:
2021-11-08



