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Genomic profiles of crocidolite-induced malignant peritoneal mesotheliomas developed in mice. Genomic profiles of crocidolite-induced malignant peritoneal mesotheliomas developed in mice

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NIAID Data Ecosystem2026-03-11 收录
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Intraperitoneal injection of crocidolite initiates malignant peritoneal mesothelioma (MM) in mice. We performed high-resolution comparative genomic hybridization to identify characterstics in the genomic profiles of crocidolite-induced MM in the mice. Overall design: The carcinogenesis protocol was performed for five groups of wild type, Dmt1-transgenic, Mth1-knockout, Mutyh-knockout and Ogg1-knockout mice. Genomes of 20 malignant mesotheliomas were profiled on Agilent 180K mouse genome CGH microarrays.

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2019-10-21
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