Detailed description of the RNA samples used for RNA seq.

Three SUS replicates were extracted from the susceptible Farm 2 in van Mol et al, 2020 [13] and P. ovis mites were collected before treatment. RESunexposed replicates were extracted from resistant Farm 5 and mites were collected before treatment. Replicates RESexposed 1–3 were from the same resistant farm, but mites were collected after treatment of the cattle with ivermectin. The RNA yields are presented together with the quality (RIN; RNA integrity number). Samples RESexposed 1 and RESexposed 2 contained equal numbers of mites (*) from the first and second collection. Sample RESexposed 3 contained 100 mites from the first collection and 50 from the second (**). (XLSX)