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RNA-seq of ATF-3 overexpressing and Neomycin control melanoma cell lines

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE152460
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The present study demonstrates that ATF-3 plays a tumor suppressing function in melanoma. Overexpression of ATF-3 in metastatic melanoma cell lines significantly inhibited their growth, migration and invasion in vitro as well as inhibited tumor growth in human melanoma xenograft mouse model in vivo. We performed RNA-seq of the melanoma cell lines A2058 and C8161 overexpressing ATF-3 by retroviral transduction and their corresponding neomycin controls.
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2020-12-15
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