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Metadata record for the manuscript: The human intermediate prolactin receptor is a mammary proto-oncogene

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Figshare2021-03-12 更新2026-04-08 收录
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https://springernature.figshare.com/articles/dataset/Metadata_record_for_the_manuscript_The_human_intermediate_prolactin_receptor_is_a_mammary_proto-oncogene/14135531/1
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<b>Summary</b><br> This metadata record provides details of the data supporting the claims of the related manuscript: “The human intermediate prolactin receptor is a mammary proto-oncogene”. The related study aimed to determine if a transforming event similar to that of truncated mouse hormone prolactin receptor (hPRLr) occurs with the hPRLr in human breast epithelial cells and to better understand the mechanism behind such transformation. Subject of data: ATCC cell lines; <i>Mus musculus</i> Sample size: n=3 for all experiments, to assess variation in experimental approach(es) and determine statistical significance; In vitro studies were replicated with two different cell lines (MCF10A vs MCF10AT, T47D vs MCF7). Trial registration number: <b>Data access</b> All data files are openly available as part of this <i>figshare </i>metadata record. A list of file names and the manuscript elements they underlie is also available in the Excel spreadsheet ‘Grible_et_al_underlying_data_list.xlsx’. All relevant scripts can be found on GihHub at: https://github.com/AmyOlex/hPRLrI_TCGA. <b>Corresponding author(s) for this study</b> Charles V. Clevenger, 1101 E. Marshall St, Sanger 4-006A, Richmond, VA 23298-0662, Phone: 804-828-0183, Fax: 804-828-9749. <br> <b>Ethics </b> Virginia Commonwealth University Institutional Animal Care and Use Committee (IACUC) together with the Division of Animal Resources (DAR)
提供机构:
J. Chuck Harrell
创建时间:
2021-03-12
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