Siddhartha2002 - Kinetic modelling of cancer therapies

Siddhartha Jain. Kinetic model for designing a cancer therapy. Cancer Cell International 2, 1 (2002).

A kinetic model has been developed to study cancer growth. Cancer growth has been considered as interaction between various independent but interacting compartments. The model considers cell growth and metastasis resulting in the formation of new tumor masses. Using certain representative parameter values, cell growth has been modeled in the absence and the presence of various cancer therapies. Based on this analysis, the critical parameters involved in cancer development have been identified. This model may thus be useful in studying and designing a cancer therapy using the data obtained from specific in vitro experiments.