PDCdb

PDCdbis a database focused on providing peptide–drug conjugate (PDC) information from multiple perspectives, particularly its pharmaceutical information and biological activities. Specifically, it collects and provides information on 2,036 PDCs along with their detailed pharmaceutical information. The database manually curates 5,050 activity data entries for 337 PDCs in vivo/in cell lines, involving 633 literature reports. These activities are identified from various clinical trial pipelines, model organisms, and patient/cell-derived xenograft models.

PDCdb是一款聚焦多维度提供肽-药物偶联物（peptide–drug conjugate，PDC）信息的数据库，尤其侧重其药学属性与生物学活性。具体而言，该数据库收录并公开了2036条肽-药物偶联物及其详细药学信息。针对其中337种肽-药物偶联物，该数据库通过人工整理得到5050条体内/细胞系活性数据条目，相关数据源自633篇学术文献。上述活性数据覆盖各类临床试验管线、模式生物以及患者来源/细胞来源异种移植模型。

搜集汇总

背景与挑战

背景概述

PDCdb是一个专注于肽-药物偶联物（PDC）的数据库，提供按PDC状态和疾病类别的搜索功能，适用于药物研发和生物医学研究。