Turnaround time computed using NCBI BLAST+ on SMP server and mpiBLAST on the HPC cluster.

The readings show that on the same number of cores i.e. 48, mpiBLAST outperforms NCBI BLAST+ by roughly 1.76 times. The maximum speedup was observed when using all 448 cores on the HPC cluster where mpiBLAST is 23.03 times faster than NCBI BLAST+. (Number of sequences in fasta file = 43758; Type: Nucleotide; No. of aligned Sequences = 1; NCBI BLAST+ executed on SMP server and mpiBLAST executed on HPC cluster; Query sequences file: ss2_Table_6_Sequences.fasta (Text S4); Search Database: NR protein database (downloaded from NCBI)).