Cryo-EM Structure of a Proteolytic ClpXP AAA+ Machine Poised to Unfold a Branched-Degron DHFR-ssrA Substrate Bound with MTX

Cryo-EM Structure of a Proteolytic ClpXP AAA+ Machine Poised to Unfold a Branched-Degron DHFR-ssrA Substrate Bound with MTX Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, ... Authors: Ghanbarpour, A, Sauer, R.T, Davis, J.H. Deposit date: 2023-12-09 Release date: 2024-10-16 Last modified: 2025-06-04 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: A proteolytic AAA+ machine poised to unfold protein substrates. Nat Commun, 15, 2024